So we see this question a lot in our industry and we thought it would be good to go over this with you. With its massive therapeutic potential, the cannabis plant is a complex marvel that features many different compounds. Of these compounds, THC (tetrahydrocannabinol) has been the most widely discussed due to its psychoactive effects — but two new molecules of this compound have recently emerged and caught the attention of both scientists and cannabis enthusiasts alike. In this article, we will compare and contrast between THC-o and THC-p in terms of their chemical structure, potency, effects on users as well as legal implications.
What is THC-o?
THC-o, also known as delta-8-THC or delta-8-tetrahydrocannabinol, is a psychoactive compound found in cannabis plants. It is structurally similar to delta-9-THC, the most common form of THC found in cannabis, but with some chemical differences. THC-o is produced from the oxidation of delta-9-THC, which occurs naturally in cannabis plants or can be created synthetically.
How THC-o is Produced
The process of producing THC-o involves exposing delta-9-THC to an oxidizing agent, such as a chemical or heat, which changes the chemical structure of the molecule. The manufacturing process begins with some AAA quality U.S. hemp, a low-THC cannabis plant that was officially allowed by the 2018 farm bill. You can use this stuff for so many things.
Initially, CBD is drawn out from raw hemp material. From there, delta-8 THC is isolated from the CBD compounds before acetic anhydride is added to convert it into its end state of THC-O acetate form. This shit takes a very skilled professional, so DO NOT try this yourself.
Potential Therapeutic Benefits of THC-o
Studies have shown that in the comparison of THC o vs THC p, that THC-o may have potential therapeutic benefits, including reducing nausea and vomiting, reducing pain and inflammation, and increasing appetite. As more and more cannabinoids become available, there still remains a need for substantial research on their effects on the human body. Good or bad we need to know.
Until cannabis is federally legalized, we cannot carry out reliable and peer-reviewed studies regarding its potential benefits. To truly understand the possible advantages of such compounds, it's essential that researchers have access to safe and legal avenues in order to further explore this field with confidence.
What is THC-p?
In 2019, Italian scientists uncovered THC-p - a powerful cannabinoid with up to 30 times the potency of its predecessor, THC. Structurally similar in many ways, THCP has one additional side chain that helps it bind more strongly to cannabinoid receptors and thereby yields more pronounced effects compared to those produced by traditional THC molecules.
How Does THCP Work?
THCP's potency relies on its capability to attach to cannabinoid receptors in the brain and nervous system. The two main types of these receptors, CB1 and CB2, have distinct functions; while CB1 is localized mainly within the brain and maintains responsibility for cannabis' psychoactive properties, their partner receptor type -CB2- is generally found in the immune system with a role devoted to subduing inflammation through cannabinoids.
When THCP binds to CB1 receptors, it produces a range of effects, including euphoria, relaxation, and altered perception. However, because THCP is more potent than THCO, its effects may be more intense and longer-lasting.
How THC-p is Produced
THC-p is produced through a natural process that occurs when cannabis plants are exposed to light. This exposure causes the breakdown of delta-9-THC, which then produces delta-10-THC. However, the process of producing THC-p in a laboratory is complex and involves multiple steps.
All cannabinoids, such as THC, CBD and THCP, originate from cannabigerolic acid (CBGA). To put it simply: CBGA goes through an enzymatic process with other acidic components of cannabis to produce tetrahydrocannabiphorolic acid (THCPA), that then slowly evolves into the precursor molecule known as THCP.
This method is called decarboxylation which takes place inside both hemp and cannabis plants.
Potential Therapeutic Benefits of THC-p
Like THC-o, THC-p's potential therapeutic benefits are still being studied, and further research is needed to fully understand its effects. Here are a lot of things these cannabinoids are thought to be able to help with.
Once again "More research is needed". See I said it again.
- THC-P is believed to help with reducing inflammation, nausea, pain relief, and muscle spasms.
- THC-O may be beneficial for treating anxiety, depression, PTSD (post traumatic stress disorder), and glaucoma.
- Both forms of THC can be used to treat symptoms of fibromyalgia and arthritis.
- THC-P is thought to be beneficial in treating certain types of cancer, including breast, prostate and brain cancer.
- THC-O is believed to help with the symptoms of multiple sclerosis such as muscle spasms and pain relief.
- THC-P may provide relief from seizures and other neurological conditions.
- THC-O has been shown to have anti-inflammatory effects, which can aid in the treatment of asthma and allergies.
- Both types of THC are believed to be helpful for treating Crohn's disease, irritable bowel syndrome (IBS) and ulcerative colitis.
- Both forms of THC can help reduce symptoms associated with Alzheimer's disease, Parkinson's disease and Huntington's disease.
THC-o vs THC-p: Chemical Differences
The chemical structure of THC-o and THC-p is different from delta-9-THC, which affects their potency and effects. THC-o has a double bond on the eighth carbon atom in its molecular structure, while THC-p has a double bond on the tenth carbon atom. These differences in chemical structure affect the way the compounds interact with the body's endocannabinoid system, which can lead to different effects.
Is THC-p Stronger than THC-o?
There is limited research on the potency of THC-p compared to THC-o, but preliminary studies suggest that THC-p is stronger than THC-o.
Early research shows THCP has a much stronger connection with the endocannabinoid system than THC. In fact, it binds up to 33 times more effectively with CB1 receptors. This means that its potency could potentially be as high as 33x greater compared to regular THC.
But...."More research is needed", you will hear that a lot in this article. Let's move on.
Now it will get you high, yes for some very high. BUT mileage may vary of course.
Effects of THC-o and THC-p
Both THC-o and THC-p have psychoactive effects that are similar to those of delta-9-THC. However, some people may experience differences in the intensity and duration of these effects due to the differences in chemical structure, solubility, and potency.
Some common effects of THC-o and THC-p may include euphoria, relaxation, increased appetite, and altered perception of time and space. However, other effects may include anxiety, paranoia, and increased heart rate. The specific effects and their intensity may vary depending on factors such as dosage, method of consumption, and individual tolerance.
Legal Status of THC o and THC p
The legal status of THC o vs THC p varies depending on location. In the United States, the legal status of these compounds is still being debated, with some states allowing their use for medical or recreational purposes, while others have banned them altogether. It is important to check the laws in your area before using THC-o or THC-p.
In short, THC-o and THC-p are groundbreaking compounds that have only recently been discovered. It's worth noting that these two beneficial components were already identified by researchers in the distant past; however, their use was restricted to a few studies.
As we continue to research the effects of cannabinoids, preliminary studies point towards potential therapeutic benefits. It's important to remember that laws and regulations regarding the use of these compounds may vary from place to place, despite their promising outlook.
So do us a favor, make sure your body can handle these cannabinoids and our potent EA Delta Signature Blends; before you go and try to hot box your room with a cloud from these ‘bliss sticks’.
Questions we get a lot about THC-o and THC-p
Can THC-o and THC-p be detected in drug tests?
Yes, THC-o and THC-p can be detected in drug tests, as they are both THC compounds. This means that using these compounds may result in a positive drug test for THC.
How long does it take to get out of your system?
THC-P and THC-o have different rates at which they leave your system, depending on factors such as body type, tolerance, and frequency of use. Generally speaking, it takes around three days for THC-P to completely leave your system, and up to 15 days for THC-o.
That said, the amount of time it takes to completely clear your system can also depend on things like how much you have consumed, the frequency of use, and other individual factors. If you are concerned about testing for THC-P or THC-o in your system, it’s best to give yourself enough time to make sure that all traces of the substance have left your body.
Is it safe to use THC-o and THC-p?
The safety of THC-o and THC-p is still being investigated, and there is limited research available on the potential long-term effects of using these compounds. Just be sure its been made by a professional with the best processes and has a real, third party data sheet that shows whats in it.
As with any cannabis product, it is important to use them responsibly and under the guidance of a healthcare professional.
Can THC-o and THC-p be used together?
Of course, you can. We have a blend with both. Our Celestial Blend is, without a doubt, equivalent to "heaven on earth." This heavenly combination of Delta8-THC, THC-o, and THC-p cannabinoids produces an unparalleled euphoric experience that relaxes the body while uplifting the soul. Customers have raved about its remarkable effects! This exceptional blend is renowned as an outstanding sleep aid by many, with its strong Indica properties of blissful body sensations, good cheerfulness, creative energy, stimulating ideas and immense stress reduction.
*These statements have not been evaluated or approved by the Food and Drug Administration and are not intended to diagnose, treat or cure any illness. Any medical advice should be taken from a medical professional.
All of the articles on this site are written by 3rd party content providers, expert bloggers, or doctors not directly affiliated with EHDelta.
Individuals should learn the risks and side effects prior to taking any Delta products. Make sure to always check with a medical professional before starting any new Delta treatment or medication that is not FDA-approved.